The 2007 GMC Truck Sierra Classic 3500 Regular Cab 4WD is a 2-door, 3-passenger full size pickup, available in 6 trims, ranging from the Work Truck Long Box DRW to the SLE1 Long Box SRW.

Upon introduction, both trims are equipped with a standard 6.0-liter, V8, 300-horsepower engine. A 5-speed manual transmission with overdrive is standard on the Work Truck Long Box DRW, and a 4-speed automatic transmission with overdrive is optional. A 4-speed automatic transmission with overdrive is standard on the SLE1 Long Box SRW.

The 2007 GMC Truck Sierra Classic 3500 Regular Cab 4WD is a carryover from 2006.